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This work describes a distinct six subunit protein complex containing HMR and LHR and analyse the effect of Hmr mutations on complex integrity and perform. It has been shown that the expression ranges of the 2 hybrid incompatibility elements Hmr and Lhr diverged in the two intently associated Drosophila species, D.

melanogaster and D. simulans, leading to an elevated stage of both proteins in interspecies hybrids. Field and laboratory experiments exhibit that F1 hybrids have a maladaptive mixture of D. yakuba conduct and D. teissieri physiology, producing extra limitations to gene flow.
This study generated replicate admixed populations between two pairs of sister species of Drosophila: D. simulans and D. mauritiana; and D. yakuba and D. santomea. However, the opposite relationship was noticed in a North American population of Drosophila melanogaster with admixed European and African ancestry.
The admixed populations had been maintained by random mating in discrete generations for over 20 generations.

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